Congenital malformations of newborns at Songklanagarind Hospital
Abstract
Objective: To determine the incidence and types of congenital anomalies in neonates delivered at Songklanagarind Hospital
Material and Methods: A retrospective study.
Results: Among a total of 27,061 neonates delivered at Songklanagarind Hospital between January 1988 and December 1999, congenital anomalies were determined in 337 neonates. The overall incidence of congenital anomalies was 1.2%. There were 249 neonates (73.9%) with isolated anomaly and 88 neonates (26.1%) with multiple anomalies. The most common cause of congenital anomalies was chromosomal abnormalities. The incidence of chromosomal abnormalities was 0.2% among which Down syndrome was the most common. Among the isolated anomaly group, musculoskeletal system abnormalities were the most common type of malformation with an incidence of 0.18% followed by facial and urogenital system anomalies, respectively. Syndromes were found in 35 neonates of the multiple anomalies group with an incidence of 0.13%. Prenatal screening for congenital anomalies found only 1.8% in pregnant women aged more than 35 years.
Conclusion: The most common cause of conge